Mycophenolate (CellCept/Myfortic)

Mycophenolate (brand names CellCept, Myfortic) is an immunosuppressant medication commonly used for autoimmune conditions in neuro-ophthalmology. It's generally well-tolerated and effective as a steroid-sparing agent.

How It Works

Mycophenolate inhibits an enzyme needed for immune cell (lymphocyte) proliferation. By reducing these cells, it dampens the immune response causing autoimmune disease.

Common Uses

• Myasthenia gravis
• NMO and MOGAD
• Uveitis
• Other autoimmune conditions

Dosing

• Usually 1000-1500mg twice daily
• May start lower and increase
• Take on empty stomach for best absorption
• Myfortic (enteric-coated) may reduce GI side effects

Side Effects

Common

• Nausea, vomiting
• Diarrhea
• Abdominal pain
• Headache

Serious (Monitor For)

• Bone marrow suppression
• Increased infection risk
• GI bleeding
• Progressive multifocal leukoencephalopathy (rare)

Critical Warning

Monitoring

• Complete blood count regularly
• Liver function tests
• Pregnancy testing before starting and during treatment
• Watch for signs of infection

Tips for Taking Mycophenolate

• Take on empty stomach (1 hour before or 2 hours after meals)
• Don't crush or chew capsules
• Space doses evenly
• Avoid antacids containing aluminum or magnesium

Frequently Asked Questions

Can I take this if I want to become pregnant?

No. You must stop mycophenolate at least 6 weeks before trying to conceive. Discuss family planning with your doctor—alternative medications may be needed.

Why do I have stomach problems?

GI side effects are common with mycophenolate. Taking it with food may help (though reduces absorption). The enteric-coated form (Myfortic) may have fewer GI effects.

How long until it works?

Full effect may take 2-3 months. Your doctor may overlap it with steroids initially.