A mineral supplement that may help mild thyroid eye disease, particularly in early stages.
Drug Class: supportive
Selenium is an essential mineral with antioxidant properties. It's studied for potential benefits in mild thyroid eye disease, particularly in early, active phases.
Key Takeaways
- Antioxidant mineral
- May help mild thyroid eye disease
- Best evidence for early, active disease
- Generally safe at recommended doses
- Not a substitute for medical treatment
Background
The EUGOGO study showed selenium may improve quality of life and slow progression in mild thyroid eye disease.
Evidence
What It May Help
- Mild, active thyroid eye disease
- May improve quality of life
- May slow progression
- Best in early disease
What It Doesn't Replace
- Not for moderate to severe disease
- Not instead of steroids when needed
- Not for established, inactive disease
Dosing
- 100 mcg twice daily
- 200 mcg total daily
- For 6 months typically
- Can be taken longer
Forms
- Sodium selenite
- Selenomethionine
- Available over the counter
- Various brands available
Safety
Generally Safe at Recommended Doses
- Upper limit: 400 mcg daily
- Don't exceed recommended dose
Toxicity Signs (Overdose)
- Hair loss
- Nail changes
- GI upset
- Garlic breath odor
- Nerve problems
Who Should Consider It
- Mild thyroid eye disease
- Active phase (early)
- Discussed with doctor
- As part of overall management
Who Should Avoid It
- Already getting enough selenium in diet
- Kidney disease (impaired excretion)
- Taking selenium from other supplements
With Other Treatments
- Can use with artificial tears
- Discuss with doctor before combining with other TED treatments
Medical Disclaimer: This information is for educational purposes only and does not replace professional medical advice.
Medically Reviewed Content
This article meets our editorial standards
- Written by:
- Hashemi Eye Care Medical Team
- Medically reviewed by:
- Board-Certified Neuro-Ophthalmologist (MD, Neuro-Ophthalmology)
- Last reviewed:
- January 30, 2025