An anti-seizure medication also used for neuropathic pain and some types of nystagmus.
Drug Class: neurological
Gabapentin (Neurontin) is an anti-seizure medication with multiple uses including neuropathic pain and certain types of nystagmus.
Key Takeaways
- Multiple uses beyond seizures
- Can reduce some types of nystagmus
- Also treats nerve pain
- Causes drowsiness initially
- Must be tapered when stopping
Common Uses
In Neuro-Ophthalmology
- Acquired nystagmus (downbeat, upbeat)
- Oscillopsia
- Superior oblique myokymia
Other Uses
- Neuropathic pain
- Seizures
- Migraine prevention
- Restless leg syndrome
How It Works
- Modulates calcium channels
- Reduces nerve excitability
- Mechanism for nystagmus not fully understood
Typical Dosing
- Start low (100-300 mg at night)
- Increase gradually
- Typical dose: 300-600 mg three times daily
- May go higher for some conditions
Side Effects
Common (Often Improve)
- Drowsiness, fatigue
- Dizziness
- Unsteadiness
- Cognitive slowing
Less Common
- Weight gain
- Swelling (edema)
- Mood changes
Starting Tips
- Start at low dose at bedtime
- Increase slowly over weeks
- Drowsiness usually improves
- Take time to find right dose
Stopping
- Must taper gradually
- Don't stop suddenly
- Withdrawal can cause seizures
- Doctor will provide schedule
For Nystagmus
- May reduce amplitude/oscillopsia
- Not effective for all types
- Congenital nystagmus usually doesn't respond
- Trial needed to assess benefit
Monitoring
- Symptoms and side effects
- Effectiveness for target condition
- Kidney function affects dosing
Medical Disclaimer: This information is for educational purposes only and does not replace professional medical advice.
Medically Reviewed Content
This article meets our editorial standards
- Written by:
- Hashemi Eye Care Medical Team
- Medically reviewed by:
- Board-Certified Neuro-Ophthalmologist (MD, Neuro-Ophthalmology)
- Last reviewed:
- January 30, 2025