A corticosteroid medication used to reduce inflammation in many neuro-ophthalmic conditions.
Drug Class: corticosteroid
Prednisone is an oral corticosteroid medication used to treat inflammation. In neuro-ophthalmology, it's used for conditions like giant cell arteritis, optic neuritis, thyroid eye disease, and other inflammatory conditions.
Key Takeaways
- Reduces inflammation by suppressing immune activity
- Used for many neuro-ophthalmic conditions
- Requires careful monitoring for side effects
- Tapering required—don't stop suddenly
- Long-term use carries significant risks
How It Works
Prednisone is converted to prednisolone in the body. It suppresses the immune system and reduces inflammation by blocking inflammatory chemicals and reducing immune cell activity.
Common Uses in Neuro-Ophthalmology
- Giant cell arteritis—high doses to prevent blindness
- Optic neuritis—oral taper after IV steroids
- Thyroid eye disease
- Myasthenia gravis
- MOGAD and NMO
- Other inflammatory conditions
Dosing
- Varies widely depending on condition
- High-dose for GCA (40-60mg daily or higher)
- Tapered gradually—never stop suddenly
- Your doctor will provide specific instructions
Long-Term Treatment Guide
If you're on long-term prednisone therapy, see our comprehensive guide for managing side effects, monitoring your health, and understanding tapering: Living with Long-Term Steroid Treatment - Patient Guide.
Side Effects
Common
- Increased appetite, weight gain
- Mood changes, insomnia
- Elevated blood sugar
- Increased blood pressure
- Fluid retention
With Prolonged Use
- Osteoporosis (bone thinning)
- Cataracts
- Increased infection risk
- Skin thinning, easy bruising
- Muscle weakness
- Adrenal suppression
Monitoring
- Blood pressure
- Blood sugar
- Bone density (with long-term use)
- Eye examinations (cataract risk)
Important Precautions
Never stop prednisone suddenly after taking it for more than a few weeks. Your body needs time to resume its own cortisol production. Sudden stopping can cause serious problems.
Frequently Asked Questions
How long will I need to take this?
Duration varies by condition. Some conditions require only short courses, while others (like GCA) may require months to years of treatment.
Why do I need to taper slowly?
Long-term steroid use suppresses your body's natural cortisol production. Tapering allows your adrenal glands to resume normal function gradually.
Can I take other medications with prednisone?
Many drug interactions exist. Always inform your doctor of all medications, including over-the-counter drugs and supplements.
Medical Disclaimer: This information is for educational purposes only and does not replace professional medical advice.
Medically Reviewed Content
This article meets our editorial standards
- Written by:
- Hashemi Eye Care Medical Team
- Medically reviewed by:
- Board-Certified Neuro-Ophthalmologist (MD, Neuro-Ophthalmology)
- Last reviewed:
- January 30, 2025