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Hashemi Eye Care - Neuroscience Institute and Research Center

Fluorescein Angiography

An imaging test using injected dye to evaluate blood flow in the retina and detect leakage or abnormal vessels.

2 min read

Fluorescein angiography (FA) is an imaging test where fluorescent dye is injected into a vein, and photographs are taken as the dye travels through the blood vessels in the eye. It reveals blood flow patterns, leakage, and vascular abnormalities.

Key Takeaways

  • Dye injected into arm vein
  • Photographs blood flow in eye
  • Detects leakage and abnormal vessels
  • Skin and urine turn yellow temporarily
  • Important for diagnosing vascular conditions

Why It's Done

What to Expect

Before the Test

  • Pupils dilated
  • IV line placed in arm
  • Inform staff of allergies

During the Test

  • Fluorescein dye injected
  • Rapid sequence of photos taken
  • Bright flashes of light
  • Photos continue for several minutes
  • Takes 15-30 minutes total

After the Test

  • Skin and urine appear yellow-orange (24-48 hours)
  • This is normal and harmless
  • Stay hydrated to flush dye

Side Effects

Common

  • Yellow discoloration of skin/urine
  • Temporary nausea (brief)

Rare

  • Allergic reaction (hives, rarely severe)
  • Extravasation (dye leaks at IV site)

What It Shows

Normal

  • Even filling of vessels
  • No leakage

Abnormal

  • Disc leakage—inflammation or papilledema
  • Delayed filling—poor blood flow
  • Hyperfluorescence—drusen, scars
  • Blocked fluorescence—hemorrhage

Neuro-Ophthalmic Uses

  • Distinguish true disc edema from drusen
  • Evaluate optic nerve ischemia
  • Assess inflammatory conditions
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