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Optic Atrophy

Pallor (pale color) of the optic disc indicating damage or death of optic nerve fibers.

Optic atrophy refers to the pale appearance of the optic disc that occurs when optic nerve fibers have been damaged or died. It's a sign of prior injury, not a diagnosis itself.

Key Takeaways

  • Pallor of the optic disc visible on examination
  • Sign of optic nerve damage—not a diagnosis
  • Many possible causes
  • Usually indicates permanent damage
  • Work up to find underlying cause

What It Looks Like

  • Pale optic disc (instead of normal pink/orange)
  • Reduced number of visible small blood vessels
  • May be segmental or complete
  • Cupping may be present
  • OCT shows nerve fiber layer thinning

Common Causes

Inflammatory

Vascular

Compressive

Hereditary

Other

  • Papilledema (long-standing)
  • Glaucoma
  • Trauma
  • Toxic/nutritional

Finding the Cause

What It Means

  • The underlying damage has occurred
  • Vision loss is usually permanent
  • Focus shifts to:
    • Finding and treating underlying cause
    • Preventing further damage
    • Low vision rehabilitation

Prognosis

Once optic atrophy develops, the nerve fiber loss is permanent. The goal is to preserve remaining vision and address any ongoing or treatable cause.

Medically Reviewed Content

This article meets our editorial standards

Written by:
Hashemi Eye Care Medical Team
Medically reviewed by:
Board-Certified Neuro-Ophthalmologist (MD, Neuro-Ophthalmology)
Last reviewed:
January 30, 2025